The safety of ranitidine has been assessed in children ages 0 to 16 years with acid-related disease and was generally well tolerated with an adverse event profile resembling that in adults.
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in a foreign, multinational, double-blind study of 602 patients with endoscopically diagnosed gastric ulcer, omeprazole 40 mg once daily, 20 mg once daily, and ranitidine 150 mg twice a day were evaluated.
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at 2 and 4 weeks both doses of prilosec were statistically superior per protocol to ranitidine, but 40 mg was not superior to 20 mg of prilosec, and at 8 weeks there was no significant difference between any of the active drugs.
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pediatric use the safety and effectiveness of ranitidine tablets, usp have been established in the age-group of 1 month to 16 years for the treatment of duodenal and gastric ulcers, gastroesophageal reflux disease and erosive esophagitis, and the maintenance of healed duodenal and gastric ulcer.
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zantac generic name ranitidine is an antagonist for h2 receptor of histamine receptors on the parietal cells of the stomach, which results in the decrease in the production the acid from these cells.
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