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because efficacy and toxicity of chloramphenicol are associated with a maximum serum concentration, peak levels one hour after the intravenous dose is given should be 10-20 mcg ml with toxicity 40 mcg ml; trough levels taken immediately before a dose should be 5-10 mcg ml.

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, chloramphenicol is used in the initial empirical treatment of children with fever and a petechial rash.

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Any remaining chloramphenicol, whether in the form of eye drops or eye ointment, should be disposed of once the course of treatment is over.

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