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In vitro enzyme inhibition data did not reveal an inhibitory effect of escitalopram on cyp3a4, -1a2, -2c9, -2c19, and -2e1.

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although trough citalopram plasma levels were unaffected, given the enzyme-inducing properties of carbamazepine, the possibility that carbamazepine might increase the clearance of citalopram should be considered if the two drugs are coadministered.

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