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10 with no drug approved specifically for treatment for pe in the us and some other countries, other ssris such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used off-label to treat pe.

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in these studies, the effectiveness of paroxetine hydrochloride compared to placebo was evaluated on the basis of 1 the proportion of responders, as defined by a clinical global impression cgi improvement score of 1 very much improved or 2 much improved , and 2 change from baseline in the liebowitz social anxiety scale lsas .

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venlafaxine appears more effective than ssris, and at least as effective as tricyclic antidepressants, in the treatment of major depression 36 often effective for depression unresponsive to ssris 2,7 high therapeutic success rate 5 effective for treatment-resistant depression 6 quick onset of antidepressant and anxiolytic activity 28,29 higher remission rates than with fluoxetine and paroxetine 13 memory improving effects 27 provides protection against a renewed occurrence of depressive symptoms recurrence prevention low potential for pharmacokinetic drug interactions due to minimal inhibition of liver cyp450 isoenzymes.

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Before starting imitrex, let your doctor know if you are also using any antidepressant like duloxetine cymbalta , escitalopram lexapro , venlafaxine effexor , sertraline zoloft , fluoxetine prozac, sarafem , citalopram celexa , fluvoxamine luvox , or paroxetine paxil .

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